Walter Koltun Selected Research

Adaptor Protein Complex 2

1/2022

AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability.

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Walter Koltun Research Topics

Disease

5	Ulcerative Colitis 10/2020 - 10/2013
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 10/2013
2	Abdominal Pain (Pain, Abdominal) 01/2022 - 04/2020
2	Crohn Disease (Crohn's Disease) 01/2020 - 03/2018
2	Pouchitis 01/2019 - 01/2018
1	Fatigue 01/2022
1	Starvation 01/2022
1	Substance-Related Disorders (Drug Abuse) 12/2021
1	Pain (Aches) 01/2021
1	Colitis 10/2020
1	Weight Loss (Weight Reduction) 04/2020
1	Inflammation (Inflammations) 11/2018
1	Dehydration (Water Stress) 07/2017
1	Diverticular Diseases 05/2017
1	Cysts 05/2017
1	Pyoderma Gangrenosum 12/2015
1	Joint Diseases (Joint Disease) 10/2013
1	Arthritis (Polyarthritis) 10/2013
1	Sclerosing Cholangitis 10/2013

Drug/Important Bio-Agent (IBA)

3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 11/2018
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2022 - 10/2020
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2022 - 04/2020
2	Dextrans (Dextran)FDA Link 01/2022 - 10/2020
2	Antidepressive Agents (Antidepressants)IBA 12/2021 - 01/2021
2	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 05/2017
1	Sirolimus (Rapamycin)FDA Link 01/2022
1	Calcitriol (Calcijex)FDA LinkGeneric 01/2022
1	Chlorpromazine (Thorazine)FDA Link 01/2022
1	ClathrinIBA 01/2022
1	CyclodextrinsIBA 01/2022
1	Mesalamine (Mesalazine)FDA LinkGeneric 01/2022
1	Phosphotransferases (Kinase)IBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	leucinalIBA 01/2022
1	SaltsIBA 01/2022
1	leucylleucine (Leu-Leu)IBA 01/2022
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 01/2022
1	Autophagy-Related Protein-1 HomologIBA 01/2022
1	Adaptor Protein Complex 2IBA 01/2022
1	CRISPR-Associated Protein 9IBA 01/2022
1	ResveratrolIBA 01/2022
1	Amiloride (Midamor)FDA LinkGeneric 01/2022
1	Opioid Analgesics (Opioids)IBA 01/2022
1	Metformin (Glucophage)FDA LinkGeneric 01/2022
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2022
1	SolutionsIBA 01/2022
1	Anti-Anxiety Agents (Anxiolytics)IBA 12/2021
1	Opiate AlkaloidsIBA 01/2021
1	AntagomirsIBA 10/2020
1	Messenger RNA (mRNA)IBA 10/2020
1	OccludinIBA 10/2020
1	Monoclonal AntibodiesIBA 03/2018
1	Ustekinumab (CNTO 1275)FDA Link 03/2018
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2017
1	CollagenIBA 05/2017
1	Intravenous Immunoglobulins (IVIG)FDA Link 12/2015
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 10/2013
1	Genetic Markers (Genetic Marker)IBA 10/2013
1	Immunoglobulin G (IgG)IBA 10/2013

Therapy/Procedure

4	Restorative Proctocolectomy 01/2019 - 10/2013
1	Intraperitoneal Injections 10/2020
1	Therapeutics 08/2017
1	Ostomy 07/2017
1	Ileostomy 10/2013